Roman A. Melnyk received his B.Sc in Biochemistry from McMaster University in 2008 and his PhD in Biochemistry under the supervision of Dr. Charles M. Deber at the University of Toronto at Sickkids in 2003. Dr. Melnyk conducted postdoctoral research at Harvard Medical School under the supervision of R. John Collier in the Department of Microbiology and Medical Genetics (2004-2006). In 2006, he accepted a position as a Senior Scientist at Merck Frosst in Montreal, where he led multi-disciplinary teams in pre-clinical drug discovery. He was involved in various drug discovery programs ranging from hypertension to HIV. In 2011, Dr. Melnyk accepted a position as a Scientist at The Hospital for Sick Children in Toronto and was appointed as an Assistant Professor in Biochemistry. His current research is focused on understanding the mechanism by which the glucosylating toxins secreted by Clostridium difficile cause disease and to use this information to develop therapeutics that neutralize their actions. In collaboration with Dr. Minassian, Dr. Melnyk’s group is also interested in approaches to treat glycogen storage diseases such as Lafora disease. Since joining Sickkids, he has been instrumental in launching the high throughput drug discovery facility embedded within the SPARC BioCentre at Sickkids. Recognitions include an Early Research Award by the Ontario Ministry of Research and Innovation in 2014.
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