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Scientific Advisory Board
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With representatives from academic and industry partners, the Scientific Advisory Board reviews progress and performance of ongoing Network projects at the GlycoNet Scientific Annual General Meeting and delivers feedback to the Research Management Committee.
Dr. Gildersleeve’s group uses chemical approaches and glycan microarray technology to study the roles of anti-carbohydrate immune responses in the development, progression, and treatment of cancer and HIV. Dr. Gildersleeve serves on the Editorial Advisory Board of ACS Central Science, the Editorial Board of the Journal of Biological Chemistry, and the Editorial Board of Cell Chemical Biology.
Dr. Lewis’ research combines sialic acid biology and bacterial pathogenesis to explore how members of the vaginal microbiome interact with each other and the host to enable colonization and cause disease. Her research has been recognized by faculty career awards from the American Heart Foundation, the March of Dimes, the International Glycoconjugate Organization and the Burroughs Wellcome Fund.
Dr. Paulson’s research program focuses on the field of glycomics, the study of sugars on a molecular level. His work, which may have implications for the treatment of cancer, influenza, and bacterial infections, has been recognized by awards including: Melville L. Wolfram Award; Karl Meyer Award; Bijvoet Medal, Bijvoet Center for Biomolecular Research, Utrecht University; Barnett Lecture, Northeastern University; and United States EPA Green Chemistry Challenge Award.
Dr. Pavliak is expert in a vaccine development with over 27 years of experience in industrial and academic vaccine research and development, encompassing the rationale design of glycoconjugate and peptide conjugate vaccine platforms for human diseases and the development of analytical control strategies for subunit vaccines, multi-component vaccine compositions, process intermediates and process introduced residuals.
Dr. Wakarchuk is a Professor from the Department of Biological Sciences at the University of Alberta. The Wakarchuk lab investigates the structure and function of the enzymes which make and degrade various glycoconjugates. This work has been enabling the chemo-enzymatic synthesis of bioactive glycoconjugates both in the laboratory and for industrial projects. The Wakarchuk lab has expertise with both mammalian and bacterial carbohydrate active enzymes for glycan remodelling applications.
Dr. Wang’s research group works to decipher the biological functions of glycoproteins and to design an effective carbohydrate-based HIV vaccine. Wang developed an efficient chemoenzymatic method to produce structurally well-defined, homogeneous glycoproteins highly demanded for functional glycomics studies.
Research in the Hsieh-Wilson group combines organic chemistry and neurobiology to understand the molecular basis of fundamental brain processes. The Hsieh-Wilson lab applies the tools of organic synthesis, biochemistry, molecular and cellular biology, biophysics and neurobiology to manipulate and understand small molecules, proteins and molecular interactions critical for neuronal communication, development, learning and memory.
Research in Dr. Young’s group is focused on the design and synthesis of novel pharmacological probes and proof-of-concept molecules for the discovery of new drug targets. Active research programs include the discovery of novel modulators of the androgen receptor for treating prostate cancer, inhibitors as anticancer therapy, and molecular probes to define the mechanism of cystic fibrosis drugs.
Canadian Glycomics Network
E5-33 Gunning/Lemieux Chemistry Centre
University of Alberta, T6G 2G2
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