Inhibiting the release of glucose into the bloodstream using a plant-based compound
Category: Research Highlight
Hybrid Antibiotic Created With Molecular ‘Rope’ Kills Resistant Bacteria
A team of scientists from the University of Manitoba created a hybrid antibiotic by tying together two different antibiotics with a molecular “rope.”
Disassembling bacteria’s protective walls
A multidisciplinary team of GlycoNet investigators is making strides towards taking down drug-resistant bacteria By Alexandria Daum A bacterial or fungal infection is difficult enough to treat, but when these infections form protective biofilms, it makes them even more stubborn. Now, the solution being explored by GlycoNet scientists is to prevent the biofilm from forming […]
Pharmacological chaperones: A promising new treatment for genetic diseases
Potential applications for Gaucher disease and Tay-Sachs disease By Alexandria Daum Every protein in a cell is sorted in the endoplasmic reticulum before it moves to other parts of the cell – think of it as a mailroom for proteins. If a piece of mail is missing an address, it’s thrown in the garbage. The […]
New U of G Research Has Disease-Fighting Potential
Two new studies led by U of G researchers showing novel ways used by pathogens to make and attach protective cell coats might open a route to new drugs for penetrating those defences and treating often-serious infections.
GlycoNet researchers discover enzymes that can aid pulmonary infections and chronic wounds
GlycoNet Network Investigator Dr. Lynne Howell and her team at The Hospital for Sick Children are developing new methods to break down the wall that protects bacteria against current therapeutic interventions.
Taking on antibacterial resistance in the 21st century
A summary of GlycoNet Network Investigators Eric Brown and Gerard Wright’s recently published work “Antibacterial drug discovery in the resistance era”
Breaking down the protective armour of the mold Aspergillus fumigatus
Collaboration between two GlycoNet researchers has led to the discovery of a novel class of enzymes and an increased understanding of how to potentially fight a common and deadly fungal infection.
Avoiding neutrophil traps: How an invasive fungus defeats the mammalian immune response
GlycoNet researcher Donald Sheppard, from the Research Institute of the McGill University Health Centre in Montreal, Canada, and colleagues set out to explore features that could facilitate infection by A. fumigatus as compared with less pathogenic Aspergillus species.
Using antagonism to identify new ways of fighting superbugs
A unique approach to studying drug combinations has given GlycoNet researchers an exciting lead in the search for new drugs to treat Staphylococcus aureus.
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