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Services Centraux

GlycoNet has centralized research facilities to provide technical expertise. These core services allow researchers to access essential scientific infrastructure at a reasonable cost that would otherwise be cost prohibitive.
 

Our Core Services

Synthèse de Glucides

The Network has one of the highest concentrations of scientists who specialize in glycan synthesis worldwide. We serve as one of the only three beta test sites for synthesizing glycans using novel automated instrumentation. We have solid infrastructure to characterize the structure-function relationships of carbohydrates and provide consulting and troubleshooting to our customers. Synthesis scale-up will be provided by our partners. Examples of carbohydrate synthesis include: oligosaccharides, building blocks, sugar nucleotides, cyclodextrins, rhamnolipids, sphingolipids, glycopeptides, Kdo glycosides, solid-phase oligosaccharide synthesis, chemoenzymatic synthesis, solid-phase synthesis using your building blocks, glycoconjugation methods, glycoconjugate synthesis, and more.

Analyse Structurale des Glycanes

We are experienced in the analysis of complex glycans and glycoproteins and can provide routine analysis. We work with each of our customer to ensure data interpretation of complex samples is to our customer’s satisfaction.

  • Caractérisation de routine des échantillons d'oligosaccharides pour le contrôle de la qualité et l'analyse
  • Détermination de structure complexe, y compris l'analyse conformationnelle à haute résolution et l’analyse de complexes protéine-glucide
  • RMN 1D/2D (300, 400, 500, 600, 700 MHz), RMN STD
  • Analyse de composition (stoechiométrie) de polysaccharides
  • Séquençage d’oligosaccharides et de glycanes
  • Détermination de structures de glycanes rares ou modifiées
  • Nano-ES, TOF MALDI/TOF, FT-ICR
  • Dynamique moléculaire des glycoprotéines et des complexes protéines-glucides
  • AMBER (GLYCAM)
  • Gaussian
  • Surface Plasma Resonance (BIAcore)
  • Microcalorimétrie
Criblage de Banque de Données de Glucides

48Hour Discovery Inc. launched as a self-sustaining company in February 2017 with the support of GlycoNet. This accelerated service is designed to help academia and industry in molecular discovery in the areas of therapeutics, diagnostics, and probe development.

At 48Hour Discovery, a client mails the protein solution for analysis and in as few as forty-eight hours later, scientists provide a list of molecules that bind to the protein. The screening services provide risk management, expert analysis and partnerships with the Network’s academic and industrial collaborators.

© CANADIAN GLYCOMICS NETWORK (GLYCONET). ALL RIGHTS RESERVED.

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