{"id":11842,"date":"2019-06-14T09:00:21","date_gmt":"2019-06-14T15:00:21","guid":{"rendered":"http:\/\/canadianglycomics.ca\/?p=11842"},"modified":"2019-06-14T09:15:52","modified_gmt":"2019-06-14T15:15:52","slug":"perspectives-from-the-next-generation-of-scientists","status":"publish","type":"post","link":"https:\/\/canadianglycomics.ca\/fr\/perspectives-from-the-next-generation-of-scientists\/","title":{"rendered":"Perspectives from the next generation of scientists"},"content":{"rendered":"<p class=\"wp-block-paragraph\"> Four GlycoNet trainees discuss how glycomics research can change the face of healthcare <\/p>\n\n\n\n<figure class=\"wp-block-image\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/canadianglycomics.ca\/wp-content\/uploads\/DSC_0184_edited-1024x683.jpg\" alt=\"\" class=\"wp-image-11843\" srcset=\"https:\/\/canadianglycomics.ca\/wp-content\/uploads\/DSC_0184_edited-1024x683.jpg 1024w, https:\/\/canadianglycomics.ca\/wp-content\/uploads\/DSC_0184_edited-300x200.jpg 300w, https:\/\/canadianglycomics.ca\/wp-content\/uploads\/DSC_0184_edited-768x512.jpg 768w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><figcaption>GlycoNet trainees (from left: Alena Pratasouskaya, Jennifer Crha, Hanna Ostapska, Ryan Sweeney) share their perspectives on the future of glycomics research.<\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><em>By Ali Chou<\/em><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">As they gathered for the fourth annual Canadian Glycomics Symposium last May, I sat down with members of GlycoNet\u2019s Trainee Association Executive Committee for a chat about the future of glycomics research. Meet Ryan, Jennifer, Hanna and Alena, four young researchers who hail from different labs across the country. They have two important things in common: their passion for science and their eagerness to engage in conversations about why science matters.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Ryan Sweeney <\/strong>is a post-doctoral researcher working in the <a href=\"https:\/\/withers.chem.ubc.ca\/\">Withers Lab<\/a> at the University of British Columbia. Fascinated by the relationship between science and creativity, Sweeney studies carbohydrates structures and their interactions with biomolecules in the body.<\/li><li><strong>Jennifer Crha<\/strong> is a Master\u2019s student working in the <a href=\"https:\/\/www.chemistry.uoguelph.ca\/cgi-bin\/uchem.exe?ac=v_page&amp;pa=DLXY1L_2\">Monteiro Lab<\/a> at the University of Guelph. Prior to her life in the lab, Crha worked in R&amp;D and quality assurance for projects in the agriculture, food sciences and the pharmaceutical industries.<\/li><li><strong>Hanna Ostapska<\/strong> is a PhD candidate working in the <a href=\"https:\/\/www.mcgill.ca\/expmed\/dr-don-sheppard\">Sheppard Lab<\/a> at McGill University. As an outdoorsy person, Ostapska grew up with a fascination for microorganisms. She started looking more closely at the link between environmental and human health after learning more about antibiotic resistance. She is taking this issue using a holistic approach.<\/li><li><strong>Alena Pratasouskaya <\/strong>is a Master\u2019s student working in the <a href=\"https:\/\/www.wlu.ca\/academics\/faculties\/faculty-of-science\/faculty-profiles\/geoff-horsman\/index.html\">Horsman Lab<\/a> at Wilfrid Laurier University. A trained teacher and speech pathologist, Pratasouskaya was moved by her patients to pursue applied science and to work on research that can derive positive health impacts for patients.<\/li><\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Life in the lab: challenges and\nopportunities<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Regardless of age or experience, most researchers would argue that it is challenging to find long-term and stable sources of funding for projects. Research takes time and most funding options will only cover the span of a few years. This creates pressure on researchers to constantly look for new avenues of financial support. Pratasouskaya explains she doesn\u2019t want to continue to climb the academic ladder for this very reason. \u201cI thought I would go for a PhD, but after seeing my professors spend a huge amount of time on grant applications, I decided that a Master\u2019s degree is sufficient for me as a technician. I can allocate most of my time to performing benchwork.\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">It\ncan be hard to explain to people outside the scientific community why projects\nneed to be funded over a long period of time. To an outsider, investing in\nresearch without a guarantee of a return on investment may seem like too much\nof a gamble. In our hyper-connected world, it is increasingly important to make\nscience accessible to the public and to demystify how investments in research\nbenefit all Canadians.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Sweeney points out that public appreciation of research, its benefits, and adequate financial support often go hand in hand. Researchers have a responsibility to educate, and advocate their own research. It is a reality that this group of researchers understands all too well.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cWe scientists need to communicate more to the public about our research. We have to make sure people understand why we are doing research,\u201d says Sweeney. \u201cAnd most of the time, using \u2018facts-listing\u2019 is not going to win buy-ins. It\u2019s about finding common values.\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">All trainees nod in unison, agreeing that simply telling people \u201cthey don\u2019t get it\u201d will not help convince them that scientific research is beneficial to society at large.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Crha is developing a vaccine to fight diarrhea caused by a food-borne pathogen. Tackling the hot-button issue of vaccination publicly can be tricky for a young scientist. But the public scrutiny and polarized opinions about vaccination do not seem to scare Crha. She understands that she has to play a role in alleviating certain people\u2019s fear of vaccines. \u201cThrough numerous encounters with people who are against vaccination, I realized that most of them held their beliefs not because they were ignorant, but because they were scared or misinformed,\u201d she says.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In the age of social media, where information is widely available, it is necessary for scientists and researchers to take part in public conversations around science, health and research. They are in a unique position to raise awareness about the benefits of research, and to share relevant and accurate information with the public.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Multidisciplinary collaboration:\u00a0a motor for scientific discovery<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">In 2017, Pratasouskaya collaborated on a project that aimed to combat antibiotic resistance in periodontal disease. It was critical to the project\u2019s success to understand the composition of a bacterial secretion that forms dental plaque. Pratasouskaya struggled to progress on that front; she isolated the bacterial secretion, but she couldn\u2019t analyze its composition in detail because she didn\u2019t have the necessary equipment, a mass spectrometer, in her lab.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cThen I met Jennifer Crha at the Canadian Glycomics Symposium,\u201d says Pratasouskaya. \u201cI learned that she routinely used a mass spectrometer as part of her research project. Later that year, I traveled to her institute as a collaborator and spent several months in the lab where she worked. Learning mass spectrometry really helped me advance my project.\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Ostapska agrees that collaboration is key. She speaks openly about the risks of conducting research in silos,particularly when trying to tackle complex and layered issues like antibiotic resistance. \u201cMicroorganisms are evolving methods to escape antibiotics. We are in a race, and their capacity to evolve is interfering with our ability to treat common infections. To prevent antibiotics from becoming ineffective, we have to collaborate with researchers from other disciplines,\u201d she says.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Ostapska\u2019s current project focuses on developing antimicrobial agents to treat lung infections that cause complications with cystic fibrosis patients. As a microbiologist, she works with chemists who synthesize sugars and produce enzymes for her research. She doesn\u2019t have the expertise to do their job, and they don\u2019t have the expertise to do hers. The more they collaborate, the quicker they can move towards solutions to treat a disease affecting thousands of Canadians.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Glycomics research: a world of\npossibility<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Our panel of young scientists all chose to pursue a career in the field for different reasons. However, they are all passionate voices for science and specifically for glycomics. Just a few decades ago, researchers realized that sugars cover every cell in our bodies and are intimately connected with health and diseases. As a result, glycomics research, a comprehensive and multidisciplinary field, is uniquely positioned to find treatments or help prevent diseases ranging from Alzheimer&#8217;s to cancer and more. And applications of glycomics also extend beyond healthcare.&nbsp; <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cGlycomics can create more jobs,\u201d says Ostapska. \u201cIt can be applied towards sustainable development. Take cellulose, a type of sugar, for example. Cellulose is biodegradable and can be used as an alternative to plastic. Another application\u2014producing biofuel from cellulose\u2014requires mass-produced enzymes to breakdown cellulose. These are all potential jobs related to glycomics research.\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Another area where glycomics is important is nutrition. A lot of common myths still need to be debunked.&nbsp; \u201cPopular beliefs assume that all carbohydrates are equal and that they are bad. For example, many know that fiber can facilitate weight loss, but they do not realize that fiber is actually a carbohydrate. Some fiber promotes digestion, while others slows the absorption of sugar into the bloodstream, thereby controlling weight and reducing cravings,\u201d says Sweeney.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">It\nis hard to know where glycomics research is heading. The field is ever growing\nand its power seems limitless. As we conclude our chat, and our four scientists\nshare their hope for the future of glycomics research, Ostapska brilliantly\nsummarizes why these researchers and others like them get up every morning.\n\u201cMany people think that science is only about scientists secluding themselves\nin the labs with machines, but that\u2019s not it,\u201d says Ostapska. \u201cFrom the very\nbeginning when we explore the world as toddlers, we learn through discovery.\nThat\u2019s what lab work is about. We learn the system, we discover how it works,\nwe ask more questions, and we learn more. It\u2019s the knowledge that we can just\nlearn a little bit more every day, and that our learning might help people,\nthat keeps us going.\u201d<\/p>","protected":false},"excerpt":{"rendered":"<p>Four GlycoNet trainees discuss how glycomics research can change the face of healthcare <\/p>","protected":false},"author":2,"featured_media":11843,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[204],"tags":[],"class_list":["post-11842","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-community","wpbf-post"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.4 - aioseo.com -->\n\t<meta name=\"description\" content=\"Four GlycoNet trainees discuss how glycomics research can change the face of healthcare\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" 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