{"id":19497,"date":"2021-11-08T16:29:30","date_gmt":"2021-11-08T23:29:30","guid":{"rendered":"https:\/\/canadianglycomics.ca\/?p=19497"},"modified":"2021-12-10T15:20:13","modified_gmt":"2021-12-10T22:20:13","slug":"new-anti-diabetic-treatment-approved-for-human-trials","status":"publish","type":"post","link":"https:\/\/canadianglycomics.ca\/fr\/new-anti-diabetic-treatment-approved-for-human-trials\/","title":{"rendered":"New anti-diabetic treatment approved for human trials"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"19497\" class=\"elementor elementor-19497\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-46e4b925 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"46e4b925\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div 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menu-item-object-page uael-creative-menu\"><a href=\"https:\/\/canadianglycomics.ca\/fr\/research\/call-for-proposals\/\" class = \"uael-sub-menu-item\">Appel \u00e0  propositions<\/a><\/li>\n\t<li id=\"menu-item-23739\" class=\"menu-item menu-item-type-post_type menu-item-object-page uael-creative-menu\"><a href=\"https:\/\/canadianglycomics.ca\/fr\/research\/research-activities-costs\/\" class = \"uael-sub-menu-item\">Eligibilit\u00e9 aux Activit\u00e9s de Recherche et aux Frais Associ\u00e9s.<\/a><\/li>\n\t<li id=\"menu-item-10688\" class=\"menu-item menu-item-type-post_type menu-item-object-page uael-creative-menu\"><a href=\"https:\/\/canadianglycomics.ca\/fr\/research\/projects\/\" class = \"uael-sub-menu-item\">Projets<\/a><\/li>\n<\/ul>\n<\/li>\n<li id=\"menu-item-19047\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children parent uael-has-submenu uael-creative-menu\"><div class=\"uael-has-submenu-container\"><a 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elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"1d9b21b3\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-60ab717c\" data-id=\"60ab717c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-27093231 elementor-widget elementor-widget-spacer\" data-id=\"27093231\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2da3de12 elementor-widget elementor-widget-text-editor\" data-id=\"2da3de12\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2 style=\"text-align: center;\">New anti-diabetic treatment approved for human trials<\/h2>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-516d26b9 elementor-widget elementor-widget-text-editor\" data-id=\"516d26b9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: center;\"><span style=\"color: #999999;\">Aalyssa Atley \u2022 Posted: November 9, 2021<\/span><\/p><p style=\"text-align: center;\">A natural compound that slows the breakdown of starch could be used to develop a more pleasant treatment for managing Type 2 diabetes.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-29671345 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"29671345\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-7c4c2844\" data-id=\"7c4c2844\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2c7e1f5a elementor-widget elementor-widget-image\" data-id=\"2c7e1f5a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"768\" height=\"768\" src=\"https:\/\/canadianglycomics.ca\/wp-content\/uploads\/Crocosmia-790-x-790-px-768x768.png\" class=\"attachment-medium_large size-medium_large wp-image-19674\" alt=\"\" srcset=\"https:\/\/canadianglycomics.ca\/wp-content\/uploads\/Crocosmia-790-x-790-px-768x768.png 768w, https:\/\/canadianglycomics.ca\/wp-content\/uploads\/Crocosmia-790-x-790-px-300x300.png 300w, https:\/\/canadianglycomics.ca\/wp-content\/uploads\/Crocosmia-790-x-790-px-150x150.png 150w, https:\/\/canadianglycomics.ca\/wp-content\/uploads\/Crocosmia-790-x-790-px-120x120.png 120w, https:\/\/canadianglycomics.ca\/wp-content\/uploads\/Crocosmia-790-x-790-px-12x12.png 12w, https:\/\/canadianglycomics.ca\/wp-content\/uploads\/Crocosmia-790-x-790-px.png 790w\" sizes=\"(max-width: 768px) 100vw, 768px\" \/>\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\">The montbretia flower is shown in bloom. MbA is isolated from the plant's underground corms (bottom right).<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-197ae4d0 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"197ae4d0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-56e2aed3 elementor-widget elementor-widget-text-editor\" data-id=\"56e2aed3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>A new anti-diabetic compound derived from a garden flower has been approved by Health Canada for Phase 1 human trials. GlycoNet researcher <a href=\"https:\/\/www.chem.ubc.ca\/stephen-withers\">Stephen Withers<\/a> anticipates that the compound could be used to develop a treatment with fewer side effects than other options currently available to those with Type 2 diabetes.<\/p><p>\u201cOur approach is to slow down the degradation of the starch component of your food, but not affect the simple sugars,\u201d says Withers, lead researcher and professor at the University of British Columbia (UBC).<\/p><p>The natural compound called Montbretin A (MbA) works by inhibiting the enzyme alpha-amylase. When MbA inhibits the alpha-amylase enzyme, starch doesn\u2019t break down immediately and instead travels down into the lower gut.<\/p><p>Normally, the alpha-amylase enzyme breaks down starch from foods such as rice and bread into complex sugars called oligosaccharides. Oligosaccharides are then further degraded by alpha-glucosidase enzymes in the gut wall, releasing glucose into the bloodstream, which causes blood sugar levels to spike in Type 2 diabetics.<\/p><p>Current drugs that target the same enzyme system usually inhibit the alpha-glucosidase enzyme, stopping the oligosaccharides or complex sugars from being broken down, and preventing the release of glucose. \u201cThe downside of these drugs is that the oligosaccharides that are shunted down provide \u2018fast food\u2019 for the gut bacteria further down, and these gut bacteria produce a lot of gas as a side product\u2026so the patient tends to suffer from diarrhea and flatulence,\u201d explains Withers. \u201cAs a consequence they do not tend to take the drug.\u201d<\/p><p>Withers expects MbA could be a drug for controlling blood glucose levels with fewer side effects than existing drugs of this class, so that Type 2 diabetics will be more likely to take it. Since MbA prevents starch from being broken down into oligosaccharides, the full starch polymer will make its way into the lower gut. \u201cThe bacteria down there can degrade that, but we anticipate they will do so much more slowly,\u201d says Withers.<\/p><h6><strong>From flower to treatment<\/strong><\/h6><p>Withers and UBC researcher Gary Brayer spent many years studying the alpha-amylase enzyme and first tried to develop a compound in the lab that could inhibit the enzyme, before turning their search to nature.<\/p><p>\u201cWe were lucky enough to get our hands on a library with a collection of extracts of different plants from around the world. We had 30,000 such extracts, and we were able to screen those extracts for potential inhibitors of the enzyme,\u201d says Withers.<\/p><p>Withers selected the most promising extract from the montbretia (Crocosmia x crocosmiiflora) flower, and worked with UBC\u00a0researcher Raymond Andersen to isolate and identify the active ingredient: MbA.<\/p><p>\u201cIn conjunction with Gary Brayer we figured out how it inhibits amylase, and in conjunction with John McNeill we did animal studies on diabetic rats and showed that it very nicely controlled blood sugar levels,\u201d says Withers.<\/p><p>Once animal studies were completed, Withers worked with J.P. Heale from UBC\u2019s University-Industry Liaison Office to approach Health Canada for permission to start human trials.<\/p><p>The Phase 1 clinical trial has been approved but it has been delayed due to COVID. The trial is set to start as soon as circumstances allow.<\/p><h6><strong>Ensuring sufficient supply<\/strong><\/h6><p>In anticipation that MbA will be successful in human trials, GlycoNet researcher and UBC professor <a href=\"https:\/\/www.msl.ubc.ca\/people\/dr-jorg-bohlmann\/\">Joerg Bohlmann<\/a>, along with his postdoctoral fellow Sandra Irmisch (now an assistant professor at Leiden University), have been tackling the problem of obtaining a secure supply of the compound on a large scale.<\/p><p>Supported by GlycoNet, Bohlmann and Irmisch have been studying how the plant makes the compound and are now working on a way to synthetically produce MbA\u2014inserting the compound-producing genes from the montbretia plant into yeast to create a \u201cfactory.\u201d Success at this approach will enable affordable, reliable production in a controlled lab environment, eliminating the risk of a shortage if the plant itself were to be affected by some disease and die off.<\/p><h6><strong>No small feat<\/strong><\/h6><p>The overall project, from the fundamental science stages to pre-clinical trials to the human trial stage now, has taken approximately 30 years of research and extensive commitment to developing a better treatment for managing Type 2 diabetes.<\/p><p>\u201cWe\u2019re excited and I\u2019d have to say pretty confident that we\u2019ll get through this phase of the clinical trial in fine shape,\u201d says Withers. \u201cMbA is very similar to a number of molecules that are in our diet, but of course you have to test it to be sure.\u201d<\/p><p>The research is supported by funds from GlycoNet and the Canadian Institutes for Health Research (CIHR). The project also involves significant contributions from Raymond Andersen, Gary Brayer, Joerg Bohlmann, John McNeill, and J.P. Heale from UBC; and Sandra Irmisch from Leiden University.<\/p><p>On November 14th, <a href=\"https:\/\/worlddiabetesday.org\/\">World Diabetes Day<\/a> aims to raise awareness of diabetes and efforts to tackle the disease, which affects over 460 million people globally.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9bf3619 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"9bf3619\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7590d33a elementor-widget elementor-widget-text-editor\" data-id=\"7590d33a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h6 style=\"text-align: center;\">Plus de <a href=\"http:\/\/canadianglycomics.ca\/fr\/news-events\/\">nouvelles de GlycoNet<\/a><\/h6>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-256dce24 elementor-widget elementor-widget-spacer\" data-id=\"256dce24\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-39e939e3 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" 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Membre<\/a><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-16 elementor-top-column elementor-element elementor-element-1482b921\" data-id=\"1482b921\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-73398db8 elementor-widget elementor-widget-text-editor\" data-id=\"73398db8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"https:\/\/canadianglycomics.ca\/fr\/research\/\"><b>Recherche<\/b><\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/research\/glyco-backgrounder\/\">introduction \u00e0 la glycomique<\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/research\/call-for-proposals\/\">Appel \u00e0  propositions<\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/research\/core-services\/\">Services Centraux<\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/research\/projects\/\">Projets<\/a><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-16 elementor-top-column elementor-element elementor-element-5a98b2c4\" data-id=\"5a98b2c4\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-635684d8 elementor-widget elementor-widget-text-editor\" 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href=\"http:\/\/canadianglycomics.ca\/fr\/training\/opportunities\/\">Opportunit\u00e9s d\u2019Emploi<\/a><\/span><br \/><span style=\"color: #ffffff;\">Ressources<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-16 elementor-top-column elementor-element elementor-element-321fd875\" data-id=\"321fd875\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ab3155c elementor-widget elementor-widget-text-editor\" data-id=\"ab3155c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/news-events\/\"><b>Nouvelles &amp; \u00c9v\u00e8nements<\/b><\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/news-events\/annual-reports\/\">Rapports Annuels<\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/curioseity\/\">CuriOSEity<\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/news-events\/media-room\/\">Salle des m\u00e9dias<\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/news-events\/newsletters\/\">Bulletins d\u2019information<\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/symposium.canadianglycomics.ca\">Symposium Canadien sur la Glycomique<\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/news-events\/upcoming-events\/\">\u00c9v\u00e8nements \u00e0 Venir<\/a><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-16 elementor-top-column elementor-element elementor-element-21af05b1\" data-id=\"21af05b1\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6dddfb45 elementor-widget elementor-widget-text-editor\" data-id=\"6dddfb45\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/contact\/\"><b>Contact<\/b><\/a><\/span><\/p><p><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"https:\/\/forum.glyconet.ca\/index.php\/Main_Page\"><b>Forum<\/b><\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/forum-help-and-faqs\/\">Aide pour le Forum et FAQ<\/a><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-16 elementor-top-column elementor-element elementor-element-6e5cf3ea\" data-id=\"6e5cf3ea\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-74b25ded elementor-widget elementor-widget-image\" data-id=\"74b25ded\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"297\" height=\"95\" src=\"https:\/\/canadianglycomics.ca\/wp-content\/uploads\/GlycoNet_logo_landscape_white-1.png\" class=\"attachment-large size-large wp-image-11877\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2a3035c0 elementor-widget elementor-widget-text-editor\" data-id=\"2a3035c0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>R\u00e9seau Canadien de la Glycomique<br \/>E5-33 Gunning\/Lemieux Chemistry Centre<br \/>University of Alberta, T6G 2G2<br \/>T\u00e9l.: 780-492-6204<br \/>T\u00e9l\u00e9c.: 780-492-4147<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-399df715 elementor-section-content-middle elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"399df715\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5874a6a7\" data-id=\"5874a6a7\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-37e618ee elementor-widget elementor-widget-text-editor\" data-id=\"37e618ee\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u00a9 R\u00e9seau Canadien de la Glycomique (GlycoNet). Tous droits r\u00e9serv\u00e9s.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>A natural compound that slows the breakdown of starch could be used to develop a more pleasant treatment for managing Type 2 diabetes.<\/p>","protected":false},"author":2,"featured_media":19508,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"elementor_canvas","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[203],"tags":[],"class_list":["post-19497","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research-highlight","wpbf-post"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.4 - aioseo.com -->\n\t<meta name=\"description\" content=\"A natural compound that slows the breakdown of starch could be used to develop a more pleasant treatment for managing Type 2 diabetes.\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"Canadian Glycomics Network\"\/>\n\t<link rel=\"canonical\" href=\"https:\/\/canadianglycomics.ca\/fr\/new-anti-diabetic-treatment-approved-for-human-trials\/\" \/>\n\t\t<meta name=\"generator\" content=\"All in One SEO (AIOSEO) 5.0.4\" \/>\n\t\t<meta property=\"og:locale\" content=\"fr_CA\" \/>\n\t\t<meta property=\"og:site_name\" content=\"Canadian Glycomics Network - Improving the quality of life of Canadians through glycomics\" \/>\n\t\t<meta property=\"og:type\" content=\"article\" \/>\n\t\t<meta property=\"og:title\" content=\"New anti-diabetic treatment approved for human trials - Canadian Glycomics Network\" \/>\n\t\t<meta property=\"og:description\" content=\"A natural compound that slows the breakdown of starch could be used to develop a more pleasant treatment for managing Type 2 diabetes.\" \/>\n\t\t<meta property=\"og:url\" content=\"https:\/\/canadianglycomics.ca\/fr\/new-anti-diabetic-treatment-approved-for-human-trials\/\" \/>\n\t\t<meta property=\"og:image\" content=\"https:\/\/canadianglycomics.ca\/wp-content\/uploads\/Crocosmia.jpg\" \/>\n\t\t<meta property=\"og:image:secure_url\" content=\"https:\/\/canadianglycomics.ca\/wp-content\/uploads\/Crocosmia.jpg\" \/>\n\t\t<meta property=\"og:image:width\" content=\"600\" \/>\n\t\t<meta property=\"og:image:height\" content=\"600\" \/>\n\t\t<meta property=\"article:published_time\" content=\"2021-11-08T23:29:30+00:00\" \/>\n\t\t<meta property=\"article:modified_time\" content=\"2021-12-10T22:20:13+00:00\" \/>\n\t\t<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n\t\t<meta name=\"twitter:title\" content=\"New anti-diabetic treatment approved for human trials - Canadian Glycomics Network\" \/>\n\t\t<meta name=\"twitter:description\" content=\"A natural compound that slows the breakdown of starch could be used to develop a more pleasant treatment for managing Type 2 diabetes.\" \/>\n\t\t<meta name=\"twitter:image\" content=\"https:\/\/canadianglycomics.ca\/wp-content\/uploads\/Crocosmia.jpg\" \/>\n\t\t<script type=\"application\/ld+json\" class=\"aioseo-schema\">\n\t\t\t{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"BlogPosting\",\"@id\":\"https:\\\/\\\/canadianglycomics.ca\\\/fr\\\/new-anti-diabetic-treatment-approved-for-human-trials\\\/#blogposting\",\"name\":\"New anti-diabetic treatment approved for human trials - Canadian Glycomics Network\",\"headline\":\"New anti-diabetic treatment approved for human trials\",\"author\":{\"@id\":\"https:\\\/\\\/canadianglycomics.ca\\\/fr\\\/author\\\/cgnadmin\\\/#author\"},\"publisher\":{\"@id\":\"https:\\\/\\\/canadianglycomics.ca\\\/fr\\\/#organization\"},\"image\":{\"@type\":\"ImageObject\",\"url\":\"https:\\\/\\\/canadianglycomics.ca\\\/wp-content\\\/uploads\\\/Crocosmia.jpg\",\"width\":600,\"height\":600,\"caption\":\"5. 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