{"id":19608,"date":"2021-11-23T08:19:11","date_gmt":"2021-11-23T15:19:11","guid":{"rendered":"https:\/\/canadianglycomics.ca\/?p=19608"},"modified":"2021-12-10T21:22:55","modified_gmt":"2021-12-11T04:22:55","slug":"enzymes-in-bacteria-found-to-have-an-unexpected-taste-for-carbs","status":"publish","type":"post","link":"https:\/\/canadianglycomics.ca\/fr\/enzymes-in-bacteria-found-to-have-an-unexpected-taste-for-carbs\/","title":{"rendered":"Enzymes in bacteria found to have an unexpected taste for carbs"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"19608\" class=\"elementor elementor-19608\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-46e4b925 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"46e4b925\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container 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menu-item-type-post_type menu-item-object-page uael-creative-menu\"><a href=\"https:\/\/canadianglycomics.ca\/fr\/news-events\/newsletters\/\" class = \"uael-sub-menu-item\">Bulletins d\u2019information<\/a><\/li>\n\t<li id=\"menu-item-11049\" class=\"menu-item menu-item-type-custom menu-item-object-custom uael-creative-menu\"><a href=\"http:\/\/www.symposium.canadianglycomics.ca\/\" class = \"uael-sub-menu-item\">Symposium Canadien sur la Glycomique<\/a><\/li>\n\t<li id=\"menu-item-10696\" class=\"menu-item menu-item-type-post_type menu-item-object-page uael-creative-menu\"><a href=\"https:\/\/canadianglycomics.ca\/fr\/news-events\/media-room\/\" class = \"uael-sub-menu-item\">Salle des m\u00e9dias<\/a><\/li>\n<\/ul>\n<\/li>\n<\/ul><\/nav>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-1d9b21b3 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"1d9b21b3\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-60ab717c\" data-id=\"60ab717c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-27093231 elementor-widget elementor-widget-spacer\" data-id=\"27093231\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2da3de12 elementor-widget elementor-widget-text-editor\" data-id=\"2da3de12\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2 style=\"text-align: center;\">Enzymes in bacteria found to have an unexpected taste for carbs<\/h2>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-516d26b9 elementor-widget elementor-widget-text-editor\" data-id=\"516d26b9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: center;\"><span style=\"color: #999999;\">Aalyssa Atley \u2022 Posted: November 23, 2021<\/span><\/p><p style=\"text-align: center;\">GlycoNet researchers studying complex enzymes gain insight into how some pathogens could potentially be targeted without antibiotics.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-29671345 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"29671345\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-7c4c2844\" data-id=\"7c4c2844\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2c7e1f5a elementor-widget elementor-widget-image\" data-id=\"2c7e1f5a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"768\" height=\"512\" src=\"https:\/\/canadianglycomics.ca\/wp-content\/uploads\/Warren-and-Al-1200-x-800-px-2-768x512.png\" class=\"attachment-medium_large size-medium_large wp-image-19700\" alt=\"\" srcset=\"https:\/\/canadianglycomics.ca\/wp-content\/uploads\/Warren-and-Al-1200-x-800-px-2-768x512.png 768w, https:\/\/canadianglycomics.ca\/wp-content\/uploads\/Warren-and-Al-1200-x-800-px-2-300x200.png 300w, https:\/\/canadianglycomics.ca\/wp-content\/uploads\/Warren-and-Al-1200-x-800-px-2-1024x683.png 1024w, https:\/\/canadianglycomics.ca\/wp-content\/uploads\/Warren-and-Al-1200-x-800-px-2-18x12.png 18w, https:\/\/canadianglycomics.ca\/wp-content\/uploads\/Warren-and-Al-1200-x-800-px-2.png 1200w\" sizes=\"(max-width: 768px) 100vw, 768px\" \/>\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\">GlycoNet investigators (left to right): Dr. Warren Wakarchuk (University of Alberta) and Dr. Alisdair Boraston (University of Victoria)<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-197ae4d0 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"197ae4d0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-56e2aed3 elementor-widget elementor-widget-text-editor\" data-id=\"56e2aed3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">GlycoNet researchers have uncovered an important piece to the puzzle of how a specific class of complex enzymes found in many bacteria function. The discovery that these enzymes need certain carbohydrate structures to operate could be the key to developing non-antibiotic treatments and aiding efforts to prevent antimicrobial resistance.\u00a0<\/span><\/p><p><span style=\"font-weight: 400;\">One of the challenges to understanding these enzymes has been their architectural complexity. \u201cWe managed to visualize the complete 1600 amino acid multimodular enzyme,\u201d says <\/span><a href=\"https:\/\/www.uvic.ca\/science\/biochem\/people\/faculty\/profiles\/boraston.php\"><span style=\"font-weight: 400;\">Alisdair Boraston<\/span><\/a><span style=\"font-weight: 400;\">, GlycoNet researcher and professor at the University of Victoria. In comparison, a typical enzyme or protein might have only 300 or 400 amino acids.<\/span><\/p><p><span style=\"font-weight: 400;\">The class of enzymes used in the initial structural <\/span><a href=\"https:\/\/www.pnas.org\/content\/118\/10\/e2019220118\"><span style=\"font-weight: 400;\">study<\/span><\/a><span style=\"font-weight: 400;\"> is quite common in bacterial pathogens and the one studied comes from a poultry pathogen, <\/span><i><span style=\"font-weight: 400;\">Clostridium perfringens, <\/span><\/i><span style=\"font-weight: 400;\">which attacks the intestine of birds. Strains of the same pathogen can affect humans, but it\u2019s a large problem in the poultry industry.\u00a0<\/span><\/p><p><span style=\"font-weight: 400;\">Examining the enzyme architecture revealed two main features. The first is that the enzyme recognizes and cleaves within the amino acid sequence (or peptide) of mucin, a component of the mucus layer surrounding the cells. The second feature is that the enzyme recognizes a specific carbohydrate structure in the mucin. Mucin is rich in carbohydrates (or glycans) that\u00a0 help it act as a barrier, which the enzyme must \u201ceat\u201d through to get to the cell. What is surprising is the extent to which these complex enzymes have adapted to needing the glycans as part of their function.\u00a0<\/span><\/p><p><span style=\"font-weight: 400;\">\u201cThis is the first group of enzymes for which both the peptide sequence and the carbohydrate structure have been shown to be required in order for degradative activity to happen,\u201d explains <\/span><a href=\"https:\/\/www.wakarchuklab.com\/\"><span style=\"font-weight: 400;\">Warren Wakarchuk<\/span><\/a><span style=\"font-weight: 400;\">, scientific director of GlycoNet and a professor at the University of Alberta.<\/span><\/p><p><span style=\"font-weight: 400;\">\u00a0\u201cWhat we&#8217;re trying to do now is link back to the question of why these bacteria want to make enzymes that are specifically targeting a carbohydrate structure on a mucin.\u201d\u00a0<\/span><\/p><p><span style=\"font-weight: 400;\">As Boraston and Wakarchuk continue to study this class of enzymes, they are interested in mapping out which carbohydrates are required by these enzymes in order to function. They have expanded the study to include approximately 30 different enzymes that are structurally related and play a role in host-bacteria interactions affecting the health of not only animals but humans as well.\u00a0<\/span><\/p><p><b>Applications in health and science<\/b><\/p><p><span style=\"font-weight: 400;\">\u201cThe hope is that if we can understand how these enzymes target things, that we might be able to develop a non-antibiotic way of dealing with some of these pathogens,\u201d says Wakarchuk.<\/span><\/p><p><span style=\"font-weight: 400;\">\u201cBecause these enzymes end up outside the cell to do their job, we don&#8217;t need to kill the bacteria. We just need to stop the enzyme.\u201d<\/span><\/p><p><span style=\"font-weight: 400;\">In terms of a therapeutic target, the main focus in the enzyme would be the catalytic domain, which causes the damage. \u201cIf you inhibited the catalytic activity, that would completely destroy its function,\u201d says Boraston.\u00a0<\/span><\/p><p><span style=\"font-weight: 400;\">A more readily implemented application of the research involving these enzymes is in mass spectrometry, a method to identify the chemical makeup of a substance. The enzymes could be used to \u201cchop up\u201d glycoproteins and, through understanding the specificity of these enzymes, scientists can interpret the fragmentation patterns to determine the mucin and carbohydrate structure.<\/span><\/p><p><b>Partnering for success<\/b><\/p><p><span style=\"font-weight: 400;\">While both Boraston and Wakarchuk have a similar scientific upbringing, they specialize in different niches needed to make this study possible.\u00a0<\/span><\/p><p><span style=\"font-weight: 400;\">\u201cI have microbiology training, I have knowledge in glycobiology and knowledge in enzymology. What I can\u2019t do is make the substrates for these enzymes,\u201d explains Boraston.<\/span><\/p><p><span style=\"font-weight: 400;\">That\u2019s where <\/span><span style=\"font-weight: 400;\">Wakarchuk comes in:<\/span><span style=\"font-weight: 400;\"> \u201cWhat\u2019s always been of interest to me is to be able to tailor make a substrate.\u201d\u00a0<\/span><\/p><p><span style=\"font-weight: 400;\">\u201cWe\u2019re expanding the list so that hopefully we can cover all the specificities of the different enzymes,\u201d says Wakarchuk.\u00a0<\/span><\/p><p><span style=\"font-weight: 400;\">\u201cIt\u2019s been a really nice synergy.\u201d\u00a0<\/span><\/p><p><span style=\"font-weight: 400;\">The research has received funding from GlycoNet.<\/span><\/p><p><i><span style=\"font-weight: 400;\">November 18-24 is <\/span><\/i><a href=\"https:\/\/www.paho.org\/en\/campaigns\/world-antimicrobial-awareness-week-2021\"><i><span style=\"font-weight: 400;\">World Antimicrobial Awareness Week<\/span><\/i><\/a><i><span style=\"font-weight: 400;\">, which aims to increase awareness of and promote best practices to prevent the spread of antimicrobial resistance.<\/span><\/i><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9bf3619 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"9bf3619\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7590d33a elementor-widget elementor-widget-text-editor\" data-id=\"7590d33a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h6 style=\"text-align: center;\">Plus de <a href=\"http:\/\/canadianglycomics.ca\/fr\/news-events\/\">nouvelles de GlycoNet<\/a><\/h6>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-256dce24 elementor-widget elementor-widget-spacer\" data-id=\"256dce24\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-39e939e3 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"39e939e3\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-16 elementor-top-column elementor-element elementor-element-2af0ce8f\" data-id=\"2af0ce8f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5cfb2509 elementor-widget elementor-widget-text-editor\" data-id=\"5cfb2509\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/about\/\"><b>\u00c0 propos<\/b><\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/about\/administration\/\">Administration<\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/about\/glyconets-corporate-policies\/\">Politiques d\u2019entreprise<\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/about\/governance\/\">Gouvernance<\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/about\/partners\/\">Partenaires<\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/people\/\">Qui nous sommes<\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/about\/become-a-member\/\">Devenir Membre<\/a><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-16 elementor-top-column elementor-element elementor-element-1482b921\" data-id=\"1482b921\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-73398db8 elementor-widget elementor-widget-text-editor\" data-id=\"73398db8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"https:\/\/canadianglycomics.ca\/fr\/research\/\"><b>Recherche<\/b><\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/research\/glyco-backgrounder\/\">introduction \u00e0 la glycomique<\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/research\/call-for-proposals\/\">Appel \u00e0  propositions<\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/research\/core-services\/\">Services Centraux<\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/research\/projects\/\">Projets<\/a><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-16 elementor-top-column elementor-element elementor-element-5a98b2c4\" data-id=\"5a98b2c4\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-635684d8 elementor-widget elementor-widget-text-editor\" data-id=\"635684d8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/training\/\"><b>Formation<\/b><\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/training\/webinar-series\/\">S\u00e9rie de webinaires<\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/training\/trainee-association\/\">Association des Stagiaires<\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/training\/internships-exchanges-awards\/\">Stages, \u00c9changes &amp; Bourses<\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/training\/opportunities\/\">Opportunit\u00e9s d\u2019Emploi<\/a><\/span><br \/><span style=\"color: #ffffff;\">Ressources<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-16 elementor-top-column elementor-element elementor-element-321fd875\" data-id=\"321fd875\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ab3155c elementor-widget elementor-widget-text-editor\" data-id=\"ab3155c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/news-events\/\"><b>Nouvelles &amp; \u00c9v\u00e8nements<\/b><\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/news-events\/annual-reports\/\">Rapports Annuels<\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/curioseity\/\">CuriOSEity<\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/news-events\/media-room\/\">Salle des m\u00e9dias<\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/news-events\/newsletters\/\">Bulletins d\u2019information<\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/symposium.canadianglycomics.ca\">Symposium Canadien sur la Glycomique<\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/news-events\/upcoming-events\/\">\u00c9v\u00e8nements \u00e0 Venir<\/a><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-16 elementor-top-column elementor-element elementor-element-21af05b1\" data-id=\"21af05b1\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6dddfb45 elementor-widget elementor-widget-text-editor\" data-id=\"6dddfb45\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/contact\/\"><b>Contact<\/b><\/a><\/span><\/p><p><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"https:\/\/forum.glyconet.ca\/index.php\/Main_Page\"><b>Forum<\/b><\/a><\/span><br \/><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"http:\/\/canadianglycomics.ca\/fr\/forum-help-and-faqs\/\">Aide pour le Forum et FAQ<\/a><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-16 elementor-top-column elementor-element elementor-element-6e5cf3ea\" data-id=\"6e5cf3ea\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-74b25ded elementor-widget elementor-widget-image\" data-id=\"74b25ded\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"297\" height=\"95\" src=\"https:\/\/canadianglycomics.ca\/wp-content\/uploads\/GlycoNet_logo_landscape_white-1.png\" class=\"attachment-large size-large wp-image-11877\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2a3035c0 elementor-widget elementor-widget-text-editor\" data-id=\"2a3035c0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>R\u00e9seau Canadien de la Glycomique<br \/>E5-33 Gunning\/Lemieux Chemistry Centre<br \/>University of Alberta, T6G 2G2<br \/>T\u00e9l.: 780-492-6204<br \/>T\u00e9l\u00e9c.: 780-492-4147<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-399df715 elementor-section-content-middle elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"399df715\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5874a6a7\" data-id=\"5874a6a7\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-37e618ee elementor-widget elementor-widget-text-editor\" data-id=\"37e618ee\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u00a9 R\u00e9seau Canadien de la Glycomique (GlycoNet). Tous droits r\u00e9serv\u00e9s.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>GlycoNet researchers studying complex enzymes gain insight into how some pathogens could potentially be targeted without antibiotics.<\/p>","protected":false},"author":2,"featured_media":19700,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[203],"tags":[36,12,7],"class_list":["post-19608","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research-highlight","tag-antimicrobials","tag-bacteria","tag-glyconet","wpbf-post"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.4 - aioseo.com -->\n\t<meta name=\"description\" content=\"GlycoNet researchers studying complex enzymes gain insight into how some pathogens could potentially be targeted without antibiotics.\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"Canadian Glycomics Network\"\/>\n\t<link rel=\"canonical\" href=\"https:\/\/canadianglycomics.ca\/fr\/enzymes-in-bacteria-found-to-have-an-unexpected-taste-for-carbs\/\" \/>\n\t\t<meta name=\"generator\" content=\"All in One SEO (AIOSEO) 5.0.4\" \/>\n\t\t<meta property=\"og:locale\" content=\"fr_CA\" \/>\n\t\t<meta property=\"og:site_name\" content=\"Canadian Glycomics Network - Improving the quality of life of Canadians through glycomics\" \/>\n\t\t<meta property=\"og:type\" content=\"article\" \/>\n\t\t<meta property=\"og:title\" content=\"Enzymes in bacteria found to have an unexpected taste for carbs - Canadian Glycomics Network\" \/>\n\t\t<meta property=\"og:description\" content=\"GlycoNet researchers studying complex enzymes gain insight into how some pathogens could potentially be targeted without antibiotics.\" \/>\n\t\t<meta property=\"og:url\" content=\"https:\/\/canadianglycomics.ca\/fr\/enzymes-in-bacteria-found-to-have-an-unexpected-taste-for-carbs\/\" \/>\n\t\t<meta property=\"og:image\" content=\"https:\/\/canadianglycomics.ca\/wp-content\/uploads\/Warren-and-Al-1200-x-800-px-2.png\" \/>\n\t\t<meta property=\"og:image:secure_url\" content=\"https:\/\/canadianglycomics.ca\/wp-content\/uploads\/Warren-and-Al-1200-x-800-px-2.png\" \/>\n\t\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t\t<meta property=\"og:image:height\" content=\"800\" \/>\n\t\t<meta property=\"article:published_time\" content=\"2021-11-23T15:19:11+00:00\" \/>\n\t\t<meta property=\"article:modified_time\" content=\"2021-12-11T04:22:55+00:00\" \/>\n\t\t<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n\t\t<meta name=\"twitter:title\" content=\"Enzymes in bacteria found to have an unexpected taste for carbs - Canadian Glycomics Network\" \/>\n\t\t<meta name=\"twitter:description\" content=\"GlycoNet researchers studying complex enzymes gain insight into how some pathogens could potentially be targeted without antibiotics.\" \/>\n\t\t<meta name=\"twitter:image\" content=\"https:\/\/canadianglycomics.ca\/wp-content\/uploads\/Warren-and-Al-1200-x-800-px-2.png\" \/>\n\t\t<script type=\"application\/ld+json\" class=\"aioseo-schema\">\n\t\t\t{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"BlogPosting\",\"@id\":\"https:\\\/\\\/canadianglycomics.ca\\\/fr\\\/enzymes-in-bacteria-found-to-have-an-unexpected-taste-for-carbs\\\/#blogposting\",\"name\":\"Enzymes in bacteria found to have an unexpected taste for carbs - Canadian Glycomics Network\",\"headline\":\"Enzymes in bacteria found to have an unexpected taste for carbs\",\"author\":{\"@id\":\"https:\\\/\\\/canadianglycomics.ca\\\/fr\\\/author\\\/cgnadmin\\\/#author\"},\"publisher\":{\"@id\":\"https:\\\/\\\/canadianglycomics.ca\\\/fr\\\/#organization\"},\"image\":{\"@type\":\"ImageObject\",\"url\":\"https:\\\/\\\/canadianglycomics.ca\\\/wp-content\\\/uploads\\\/Warren-and-Al-1200-x-800-px-2.png\",\"width\":1200,\"height\":800,\"caption\":\"9. 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