{"id":8558,"date":"2017-12-18T14:24:59","date_gmt":"2017-12-18T21:24:59","guid":{"rendered":"http:\/\/canadianglycomics.ca\/?p=8558"},"modified":"2019-08-01T10:45:39","modified_gmt":"2019-08-01T16:45:39","slug":"plantform-research-partnership-receives-glyconet-grant","status":"publish","type":"post","link":"https:\/\/canadianglycomics.ca\/fr\/plantform-research-partnership-receives-glyconet-grant\/","title":{"rendered":"PlantForm research partnership receives GlycoNet grant"},"content":{"rendered":"

GUELPH, Ont., <\/strong>Dec. 13, 2017\u2014A research partnership between PlantForm Corporation<\/strong><\/a> and scientists at Ryerson University and the University of Victoria has been awarded a GlycoNet Collaborative Team Grant from the Canadian Glycomics Network (GlycoNet<\/strong><\/a>).<\/p>\n

The funding will support work led by Dr. Warren Wakarchuk at Ryerson towards advancing a plant-made butyrylcholinesterase (BuChE) drug candidate for broad-spectrum protection against nerve agents such as sarin and soman.<\/p>\n

For this project, Wakarchuk will be collaborating with UVic\u2019s Dr. Alisdair Boraston to use in vitro<\/em>glycosylation \u2014 the process of attaching carbohydrate \/ sugar molecules to proteins in order to modify their pharmacokinetic properties \u2014 to help PlantForm scale up BuChE production.<\/p>\n

\u201cPlantForm is excited about advancing our in vitro<\/em> glycosylation technology with Dr. Wakarchuk and Dr. Boraston,\u201d said Dr. Don Stewart, PlantForm\u2019s President and CEO. \u201cThis project will expand our capabilities toward producing BuChE on a commercial scale.\u201d<\/p>\n

\u201cWe are looking forward to continued development of this glycosylation technology with PlantForm for therapeutic protein production,\u201d Dr. Wakarchuk said.<\/p>\n

PlantForm has produced recombinant BuChE using its high-yield, low-cost tobacco-plant-based vivo<\/em>XPRESS\u00ae<\/sup> platform and conducted preclinical tests in an animal model. This new project with Dr. Wakarchuk aims to improve the glycosylation technology for BuChE and other next-generation protein drug candidates.<\/p>\n

The GlycoNet funding of $226,000 is matched by cash and in-kind contributions from PlantForm, for a total of approximately $450,000 for the two-year project, which begins January 2018.<\/p>\n

GlycoNet is a network of over 100 researchers at 29 Canadian universities and research institutes, along with industry and international partners, funded by the federal government through the Networks of Centres of Excellence. GlycoNet\u2019s research program focuses on examining the effects of carbohydrates on biological systems in relation to five themes: antimicrobials, chronic diseases, diabetes and obesity, rare genetic diseases and therapeutic proteins and vaccines.<\/p>\n

About PlantForm Corporation<\/strong> (www.plantformcorp.com<\/strong><\/a>)<\/p>\n

PlantForm Corporation is a biopharmaceutical company focused on the rapid development and production of specialty antibody and protein drugs using the company\u2019s  proprietary vivo<\/em>XPRESS\u00ae<\/sup>platform<\/strong><\/a>. The plant-based vivo<\/em>XPRESS\u00ae <\/sup>system makes it easier, faster and less expensive to produce approved biologic drugs for novel indications and new markets. The company\u2019s pipeline includes trastuzumab for a novel indication in nerve regeneration, a biosimilar version of Lucentis\u00ae and other niche indication drugs. Learn more.<\/strong><\/a><\/div>\n
<\/div>\n
This article originally appeared on the PlantForm website on December 13th, 2017: http:\/\/www.plantformcorp.com\/file.aspx?id=b74c704e-7bb9-4b4f-85a9-a2755ed0bb9c<\/a><\/em><\/div>\n

For more information, please contact:<\/strong><\/p>\n\n\n\n
Don Stewart<\/strong>
\nPresident and CEO
\ndon.stewart@plantformcorp.com<\/a>
\n+1 416-452-7242<\/td>\n		Stacey Curry Gunn<\/strong>
\nDirectrice des communications
\nstacey.curry.gunn@plantformcorp.com<\/a>
\n+1 519-827-1131<\/td>\n<\/tr>\n<\/tbody>\n<\/table>","protected":false},"excerpt":{"rendered":"

GUELPH, Ont., Dec. 13, 2017\u2014A research partnership between PlantForm Corporation and scientists at Ryerson University and the University of Victoria has been awarded a GlycoNet Collaborative Team Grant from the Canadian Glycomics Network (GlycoNet). The funding will support work led by Dr. Warren Wakarchuk at Ryerson towards advancing a plant-made butyrylcholinesterase (BuChE) drug candidate for broad-spectrum protection against […]<\/p>\n","protected":false},"author":2,"featured_media":11368,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[200],"tags":[],"class_list":["post-8558","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-press-release","wpbf-post"],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t