Core Services
GlycoNet has centralized research facilities to provide technical expertise. These core services allow researchers to access essential scientific infrastructure at a reasonable cost that would otherwise be cost prohibitive.
For more information or to request a quote for glycan synthesis or structure analysis , please contact the Core Services at coreservices@glyconet.ca.
Our Core Services
Carbohydrate Synthesis
The Network has one of the highest concentrations of scientists who specialize in glycan synthesis worldwide. We serve as one of the only three beta test sites for synthesizing glycans using novel automated instrumentation. We have solid infrastructure to characterize the structure-function relationships of carbohydrates and provide consulting and troubleshooting to our customers. Synthesis scale-up will be provided by our partners. Examples of carbohydrate synthesis include: oligosaccharides, building blocks, sugar nucleotides, cyclodextrins, rhamnolipids, sphingolipids, glycopeptides, Kdo glycosides, solid-phase oligosaccharide synthesis, chemoenzymatic synthesis, solid-phase synthesis using your building blocks, glycoconjugation methods, glycoconjugate synthesis, and more.
Glycan Structure Analysis
We are experienced in the analysis of complex glycans and glycoproteins and can provide routine analysis. We work with each of our customer to ensure data interpretation of complex samples is to our customer’s satisfaction.
- Routine characterization of oligosaccharide samples for QC and analysis
- Complex structure determination, including high-resolution conformational analysis and protein-carbohydrate complexes
- 1D/2D NMR (300, 400, 500, 600, 700 MHz), STD-NMR
- Compositional analysis (stoichiometry) of polysaccharides
- Oligosaccharide/Glycan sequencing
- Determination of unusual or modified glycan structures
- Nano-ES, MALDI TOF/TOF, FT-ICR
- Molecular dynamics of glycoproteins and protein-carbohydrate complexes
- AMBER (GLYCAM)
- Gaussian
- Surface Plasma Resonance (BIAcore)
- Microcalorimetry
Library Screening
48Hour Discovery Inc. launched as a self-sustaining company in February 2017 with the support of GlycoNet. This accelerated service is designed to help academia and industry in molecular discovery in the areas of therapeutics, diagnostics, and probe development.
At 48Hour Discovery, a client mails the protein solution for analysis and in as few as forty-eight hours later, scientists provide a list of molecules that bind to the protein. The screening services provide risk management, expert analysis and partnerships with the Network’s academic and industrial collaborators.
Canadian Glycomics Network
E5-33 Gunning/Lemieux Chemistry Centre
University of Alberta, T6G 2G2
Tel: 78-492-6204
Fax: 780-492-4147
© CANADIAN GLYCOMICS NETWORK (GLYCONET). ALL RIGHTS RESERVED.
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