Webinar Series
GlycoNet/ACS Joint Webinars:
June, 2021
Past GlycoNet Webinars
GlycoNet offers webinars on diverse topics ranging from scientific research to professional development, technical workshops, and focused seminars for the science community. In September 2020, GlycoNet has joined forces with the Carbohydrate Chemistry Division of American Chemical Society to host webinars featuring renowned researchers across North America and Europe. In addition to Q&A period, each event is followed by an informal “networking session” at the end of the presentations, giving the audience opportunities to learn more about the presenters and their research.
Upcoming Webinars
S4E19: June 16, 11 am – 12:30 pm MT | Register Here
Lisa Willis
Assistant Professor, University of Alberta
Glycoengineering polysialic acid: insights into sex differences in human polysialic acid
Dr. Willis received her B.Sc. in Biochemistry from the University of Victoria and Ph.D. in Molecular and Cellular Biology in the lab of Dr. Chris Whitfield at the University of Guelph. She did her postdoctoral fellowship with Dr. Mark Nitz in the Department of Chemistry at the University of Toronto, where she received the prestigious Banting Postdoctoral Fellowship. In 2019, she started as an Assistant Professor in the Department of Biological Sciences at the University of Alberta. She is also an Adjunct Professor in the Department of Medical Microbiology and Immunology at UofA.
Nichole Pedowitz
Graduate Student (Pratt Lab), University of Southern California
MYPT1 O-GlcNAcylation regulates sphingosine-1-phosphate
Nichole J. Pedowitz is a graduate student in the Pratt Lab at the University of Southern California. She received her B.S. in Chemistry and Biological Sciences from the University of Maryland in 2012, performing undergraduate research with Daniel Falvey on the synthesis and kinetics photoreleasable protecting groups. Her work in the Pratt lab focuses on designing and synthesizing analog-based inhibitors of O-GlcNAc transferase and studying the role of O-GlcNAcylation on fibroblast motility and differentiation.
S4E20: June 30, 11 am – 12:30 pm MT | Register Here
Jiaoyang Jiang
Associate Professor, University of Wisconsin-Madison
How can one regulates so many? Structural features of O-GlcNAcase in substrate recognition
Dr. Jiaoyang Jiang is an Associate Professor in the Pharmaceutical Sciences Division at the University of Wisconsin-Madison. She earned her Ph.D. in chemistry from Brown University with Prof. David Cane, where she elucidated natural product biosynthetic pathways in bacteria. Following that, Dr. Jiang performed postdoctoral research at Harvard Medical School in the laboratory of Prof. Suzanne Walker, where she characterized the glycosyltransferase and the unique proteolytic activities of human O-GlcNAc transferase (OGT), and discovered a small molecule with novel mechanism of inhibition. In 2013, Dr. Jiang started her appointment as an Assistant Professor of Drug Discovery at the UW-Madison School of Pharmacy. She was promoted to Associate Professor in 2019. Dr. Jiang has received a number of awards, including Distinguished Faculty Award, Vilas Faculty Early Career Investigator Award, David Y. Gin New Investigator Award, and Young Chemical Biologist Award. Her research interests span the gap between chemistry and biology. Her group is currently developing innovative strategies and tools to characterize the substrate recognition and functional regulation of O-GlcNAc cycling enzymes (OGT and OGA) in health and disease.
Revathi Reddy
Graduate Student (Derda Lab), University of Alberta
The ABCs of profiling ABO antibodies using Liquid Glycan Array
Revathi is an MSc candidate, soon to graduate from Dr. Ratmir Derda’s group at the Department of Chemistry, University of Alberta. Her research focuses on developing phage-display enabled tools to profile anti-glycan antibodies in the human serum.
Follow us on social media to get our latest announcements:
| No. overall | No. in season | Speakers & titles |
|---|---|---|
| 1 | 1 |
Dr. Christopher Cairo, Associate Professor, University of Alberta Inhibitors of human neuraminidase enzymes as probes in glycobiology Mirat Sojitra, Graduate Student, University of Alberta Genetically encoded multivalent liquid glycan array (LiGA) |
| 2 | 2 |
Dr. Andrew Lees, Founder and Scientific Director, Fina Biosolutions Simplifying conjugation: ready to conjugate CRM197 carrier protein |
| 3 | 3 |
Dr. Robert Woods, Professor, University of Georgia 3D models of glycosylated SARS-CoV-2 protein suggest challenges for vaccine development Dr. Jolene Garber, Post-Doctoral Fellow, University of British Columbia Okanagan Campylobacter jejuni chemotaxis and metabolism of fucose |
| 4 | 4 |
Dr. Lori Yang, CEO & CSO, Lectenz Bio Lectenz and GlycoSense: novel tools for glycan detection and analysis |
| 5 | 5 |
Dr. Matt Macauley, Assistant Professor, University of Alberta Modulation of microglia by the glycan-binding protein CD33 Carla Eymard, Graduate Students, Institut de recherches cliniques de Montreal From free radical chemistry to novel classes of bioactive modified furanosides |
| 6 | 6 |
Dr. Anne Krook, Practical Workplace Advice A guide to non-academic job search |
| 7 | 7 |
Dr. Karla Williams, Assistant Professor, University of British Columbia Polysialic acid as a prognostic marker in breast cancer Sadia Rahmani, Graduate Student, Ryerson University O-GlcNAc modification affects clathrin-coated pit assembly and efficiency at the plasma membrane |
| 8 | 8 |
Panel Discussion ft. Drs. David Vocadlo, Stephanie White, and Kaley Wilson What I wish I knew: a chat with researchers, patent experts and entrepreneurs |
| 9 | 9 |
Dr. Lynne Howell, Professor, The Hospital for Sick Children Exopolysaccharide biosynthesis Dr. Ryan Sweeney, Post-Doctoral Fellow, University of Alberta Development of an active site titration reagent for amylases |
| 10 | 10 |
Andrew MacIsaac, CEO, Applied Pharmaceutical Innovation Navigating commercial development with API |
| 11 | 11 |
Dr. Molly Shoichet, Professor, University of Toronto Polysaccharide hydrogels enable local drug and cell delivery Akay Akohwarien, Research Technician, University of Saskatchewan Designing novel chemical tools to study β-glucocerebrosidase: a relevant biomarker and therapeutic target in Parkinson's Disease |
| 12 | 12 |
Sabrina Sassi, TEDx Speaker Leveraging TED to spread your research ideas: how and why researchers are doing it |
Season 2 (July – August 2020)
| No. overall | No. in season | Speakers & titles |
|---|---|---|
| 13 | 1 |
Dr. Parastoo Azadi, Executive Director, Analytical Services, Complex Carbohydrate Research Centre Glycobiology of SARS-CoV2 and its implications for vaccine development Dr. Supriya Dey, Post-Doctoral Fellow, Harvard University Programmable one-pot synthesis of heparin and heparin-related anticoagulants |
| 14 | 2 |
Dr. Robert Ben, Professor, University of Ottawa Improving the efficacy of modern cellular therapies Dr. François Le Mauff, Post-Doctoral Fellow, McGill University Structural and biochemical characterization of the exopolysaccharide deacetylase Agd3 required for aspergillus fumigatus biofilm formation |
| 15 | 3 |
Dr. David Pamer, Professor, University of Saskatchewan Writing an effective grant proposal |
| 16 | 4 |
Dr. David Kwan, Assistant Professor, Concordia University A set of chemical biology tools to probe and inhibit cellular glycosyltransferases Shermaine Sy, B.Sc, University of Alberta Development of a bead-based assay for ABO antibody detection: creating a new tool for the clinical laboratory |
| 17 | 5 |
Drs. Kate Pratt and Jonathon Simmons, Academic Success Centre, University of Alberta A workshop for scientific writers |
| 18 | 6 |
Dr. Chris Phenix, Assistant Professor, University of Saskatchewan Chemical tools for studying glucosidase activity in complex biological samples F. Ifthiha Mohideen, Graduate Student, Concordia University An engineered in vitro enzymatic pathway for the anticancer anthracycline deoxysugars: TDP-L-acosamine and TDP-L-daunosamine |
| 19 | 7 |
Dr. Rebecca Davis, Associate Professor, University of Manitoba Computational approaches for designing small molecule inhibitors |
| 20 | 8 |
Dr. Robert Britton, Professor, Simon Fraser University De novo synthesis of nucleoside analogues for medicinal chemistry purposes Dr. Kristen Low, Post-Doctoral Fellow, Agriculture and Agri-Food Canada Bioprospecting CAZymes from intestinal microbiomes for the tailored degradation of non-starch dietary polysaccharides |
Season 3 (September – December 2020)
| No. overall | No. in season | Speakers & titles |
|---|---|---|
| 21 | 1 |
Dr. Lara Mahal, Professor, University of Alberta Exploring the roles of glycosylation in infection and immunity Dr. Peter Rahfeld, Research Associate, University of British Columbia From gut to blood: how to make universal donor blood |
| 22 | 2 |
Dr. Mary Cloninger, Professor, Montana State University Lactose-functionalized dendrimers and dendritic polyglycerols for binding to galectin-3 Dr. Pumtiwitt McCarthy, Associate Professor, Morgan State University Bacterial capsule polymerases as tools to improve human health |
| 23 | 3 |
Dr. Warren Wakarchuk, Professor, University of Alberta Protein engineering of 21st century drugs through the application of synthetic biology Dr. Landon Edgar, Post-doctoral fellow, Scripps Research Invigorating T cells through carbohydrate editing |
| 24 | 4 |
Dr. Theresa M. Reineke, Professor, University of Minnesota Glycopolymers promote in vivo and ex vivo delivery of functional nucleic acids Dr. Jodi Hadden-Perilla, Assistant Professor, University of Delaware The fuzzy boundaries of carbohydrate binding sites |
| 25 | 5 |
Dr. Mark Nitz, Professor, University of Toronto Exploring a low affinity probe for the biofilm-associated poly-N-acetylglycosamine exopolysaccharide Dr. Sandra Irmisch, Research Associate, University of British Columbia A novel anti-diabetic compound from plants: biosynthesis, gene discovery, and metabolic engineering of montbretin A |
| 26 | 6 |
Dr. Mingdi Yan, Professor, University of Massachusetts Lowell Carbohydrate-conjugated fluorescence turn-on azide probes for imaging cells and bacteria Dr. Jessica Kramer, Assistant Professor, University of Utah Synthetic mucins: from new chemical routes to engineered cells |
| 27 | 7 |
Dr. David Vocadlo, Professor, Simon Fraser University Fluorescence-quenched substrates for monitoring glycoside hydrolase activities in mammalian cells Dr. Simonetta Sipione, Professor, University of Alberta Gangliosides in neurodegeneration and neuroinflammation |
Season 4 (January – June 2021)
| No. overall | No. in season | Speakers & titles |
|---|---|---|
| 28 | 1 |
Dr. Geert-Jan Boons, Professor, University of Georgia Probing receptor and co-receptor specificities of coronaviruses using chemo-enzymatic synthesis and glycoarray technology Dr. Hien Nguyen, Professor, Wayne State University Discovery of sulfated glycopolymers as potent inhibitors of heparanase and SARS-CoV-2 |
| 29 | 2 |
Dr. Jennifer Kohler, Associate Professor, University of Texas Southwestern Medical Center Intestinal fucose, in sickness and in health Catherine Alex, Graduate Student, University of Missouri-St. Louis Methodologies for stereocontrolled mannosylation with acidic and/or aminosugars |
| 30 | 3 |
Dr. Jia Niu, Assistant Professor, Boston College A general approach to early-stage O-sulfation of carbohydrates and peptides Erum Razvi, Graduate Student, SickKids Hostpial Identifying the role of the Pseudomonas aeruginosa PelA hydrolase in Pel polysaccharide biosynthesis |
| 31 | 4 |
Dr. Chantelle Capicciotti, Assistant Professor, Queen's University Glycan remodelling with chemical tools to probe glycan-protein interactions Jiayi Li, Graduate Student, Wayne State University Phenanthroline-catalyzed glycosylation: expansion of substrate scope and investigation of mechanism |
| 32 | 5 |
Dr. John Hanover, Chief, Laboratory of Cell and Molecular Biology, NIDDK at National Institutes of Health O-GlcNAc and Disease Matthew Deen, Graduate Student, Simon Fraser University A light in the darkness: GBA1-FQ6 a new tool for studying glucocerebrosidase a Parkinson’s disease associated glycoside hydrolase |
| 33 | 6 |
Dr. Sabine Flitsch, Professor, Manchester Institute of Biotechnology Synthetic and analytical tools for glycobiology Shaochi Wang, Graduate Student, University of Maryland Development of colorimetric and fluorometric oligosaccharide probes enabling high-throughput screening for glycosyl hydrolase enzymes |
| 34 | 7 |
Dr. Charlie Fehl, Assistant Professor, Wayne State University Real-time chemical tools for dynamic O-GlcNAc glycoprotein functions Dr. Adam Forman, Post-doctoral Researcher, University of Toronto Development of substrates to characterize PgaB, a hydrolase involved in the synthesis of the biofilm exopolysaccharide dPNAG |
| 35 | 8 |
Dr. Kelly McNagny, Professor, University of British Columbia CD34-type sialomucins: general regulators of cell adhesion and migration and targets for cancer immunotherapy Dr. Jicheng Zhang, Post-doctoral Researcher, Wayne State University Trisaccharides with specific sulfation sequences in modulating heparanase activity |
| 36 | 9 |
Dr. Kamil Godula, Associate Professor, University of California San Diego Functional polymeric glycomaterials for regulating stem cell differentiation Kristina Klobucar, Graduate Student, McMaster University A chemical screen for vancomycin antagonism uncovers probes of the Gram-negative outer membrane |
| 37 | 10 |
Dr. Christoph Rademacher, Professor, University of Vienna Application of glycomimetics for the development of topical vaccines Jonathan Quirke, Graduate Student, University of Georgia Glycosidase and glycosyltransferase transition state stabilization through substrate side chain restriction |
| 38 | 11 |
Dr. Nicola Pohl, Professor, Indiana University Bloomington How to Make Glycan Synthesis FAIR* (* Findable, Accessible, Interoperable and Reusable) Hanna Ostapska, Graduate Student, McGill University Exopolysaccharides in co-operative biofilm formation by A. fumigatus and P. aeruginosa |
| 39 | 12 |
Dr. Wade Abbott, Research Scientist, Agriculture and Agri-Food Canada Glyco-enabling tools for study of microbial glycan metabolism in agriculture Daniel Ramirez, Graduate Student, Harvard University Engineering a proximity-directed OGT to control O-GlcNAc signaling |
| 40 | 13 |
Dr. Ben Swarts, Associate Professor, Central Michigan University Commandeering mycobacterial carbohydrate metabolism for applications in tuberculosis research Emily Rodrigues, Graduate Student, University of Alberta Leveraging avidity of Siglec-ligand interactions with a versatile soluble Siglec scaffold |
| 41 | 14 |
Dr. Lori West, Professor, University of Alberta Bringing 21st century tools for ABO antibody detection into the clinical laboratory Courtney Kondor, Graduate Student, Wayne State University Development of photo-controlled sugar labeling reagents to track disease processes |
| 42 | 15 |
Dr. Catherine Grimes, Professor, University of Delaware Peptidoglycan and you, perfect together? Dr. Abhishek Bhatatcherjee, Post-Doctoral Researcher, University of Alberta Role of CD33 isoforms in Alzheimer’s Disease susceptibility |
| 43 | 16 |
Dr. Alisdair Boraston, Professor, University of Victoria O-glycopeptidases: the complex substrate recognition determinants of peptidases with a sweet tooth Adam Kositzke, Graduate Student, University of Wisconsin-Madison Elucidating the substrate binding mode of O-GlcNAc transferase toward O-GlcNAcase using electrophilic probes |
| 44 | 17 |
Dr. Tianning Diao, Associate Professor, New York University Photoredox C-glycosylation of glycosyl esters Dr. Nikki Salmond, Post-doctoral Researcher, University of British Columbia Extracellular vesicle-associated glycans for the diagnosis and prognostication of breast cancer |
| 45 | 18 |
Dr. Samy Cecioni, Assistant Professor, University of Montreal Chemical strategies for live cell quantitative imaging of glycoside hydrolase activity Dr. Yun Ge, Post-Doctoral Researcher, Harvard University Target protein deglycosylation in living cells by a nanobody-fused split O-GlcNAcase |
| 46 | 19 |
Dr. Sander van Kasteren, Associate Professor, University of Leiden Carbohydrate-Lectin Interactions – A love/hate story Sarah Zaytsoff, Graduate Student, University of Alberta and Agriculture and Agri-Food Canada The role of the intestinal microbiota and mucus in disease resistance to necrotic enteritis in chickens |
Canadian Glycomics Network
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